Dalacin T Use In Pregnancy & Lactation

Pregnancy: Oral and subcutaneous reproductive toxicity studies in rats and rabbits revealed no evidence of impaired fertility or harm to the fetus due to clindamycin, except at doses that caused maternal toxicity. Animal reproduction studies are not always predictive of human response.
In clinical trials with limited number of pregnant women, the systemic administration of clindamycin during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities. However, there are no adequate and well-controlled studies using clindamycin in pregnant women during the first trimester of pregnancy and this drug should be used during pregnancy only if clearly needed.
Nursing Mothers: It is not known whether clindamycin is excreted in human breast milk following use of DALACIN T. Clindamycin has been reported to appear in human breast milk in ranges from <0.5 to 3.8 mcg/mL following systemic use.
Clindamycin has the potential to cause adverse effects on the breastfed infant's gastrointestinal flora such as diarrhea or blood in the stool, or rash. If clindamycin is required by a nursing mother, it is not a reason to discontinue breastfeeding, but an alternate drug may be preferred. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for clindamycin and any potential adverse effects on the breastfed child from clindamycin or from the underlying maternal condition.